MolNFT v1 · #158539 · protein

Structure of the C-terminal helical repeat domain of eukaryotic elongation factor 2 kinase (eef-2K)

6NX4: “Structure of the C-terminal helical repeat domain of eukaryotic elongation factor 2 kinase (eef-2K)”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1 #158539 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6NX4
Type: protein
Length: 167 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Eukaryotic elongation factor 2 kinase
EC: 2.7.11.20
UniProt: O00418
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 54% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Eukaryotic elongation factor 2 kinase (EC 2.7.11.20)	protein	167	54% helix, 0% strand	O00418

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	135	0.41	0.75	24	empty

Compared structures

6NX4 · Structure of the C-terminal Helical Repeat Domain of Eukaryotic Elongation Factor 2… · the same entry in another collection · chain A against A, TM-score 1.00
O00418 · AlphaFold monomer V2.0 prediction for eukaryotic elongation factor 2 kinase (O00418) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00418
Elsewhere: RCSB PDB 6NX4 · PDBe 6NX4 · UniProt O00418

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