MolNFT v1 · #158460 · protein

Human guanylate kinase

6NUI: “Human guanylate kinase”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #158460 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6NUI
Type: protein
Length: 198 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Guanylate kinase
EC: 2.7.4.8
UniProt: Q16774
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 43% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Guanylate kinase (EC 2.7.4.8)	protein	198	43% helix, 18% strand	Q16774

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.32	0.77	20	empty

Compared structures

6NUI · Human Guanylate Kinase · the same entry in another collection · chain A against A, TM-score 1.00
Q16774 · AlphaFold monomer V2.0 prediction for guanylate kinase (Q16774) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16774
Elsewhere: RCSB PDB 6NUI · PDBe 6NUI · UniProt Q16774

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