MolNFT v1 · #158208 · protein
The structure of human liver pyruvate kinase, hlpyk-D499N, in complex with fru-1,6-bp
6NN4: “The structure of human liver pyruvate kinase, hlpyk-D499N, in complex with fru-1,6-bp”. X-ray diffraction, 2 ligands (FBP, PEP). MolNFT v1 #158208 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6NN4
- Type
- protein
- Length
- 1,665 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P30613
- Ligands
- FBP, PEP
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 418 | — | P30613 |
| B | — | protein | 414 | — | P30613 |
| C | — | protein | 419 | — | P30613 |
| D | — | protein | 414 | — | P30613 |
Ligands and binding sites
- FBP · 1,6-di-O-phosphono-beta-D-fructofuranose · ligand · 4 copies · chains A, B, C, D
- PEP · Phosphoenolpyruvate · ligand · 4 copies · chains A, B, C, D
- EDO · 1,2-ethanediol · additive · 7 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6NN4 · The structure of human liver pyruvate kinase, hLPYK-D499N, in complex with Fru-1,6-BP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30613
- Elsewhere: RCSB PDB 6NN4 · PDBe 6NN4 · UniProt P30613
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.