MolNFT v1 · #158046 · protein

Crystal structure of human REV7-ran complex

6NIF · HREV7, GTP-binding nuclear protein ran, HREV3 fusion: “Crystal structure of human REV7-ran complex”. X-ray diffraction, 1 pocket (best druggability 0.40). MolNFT v1 #158046 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6NIF
Type: protein
Length: 212 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HREV7, GTP-binding nuclear protein ran, HREV3 fusion
EC: 2.7.7.7
UniProt: Q9UI95, F5H018, O60673
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	HREV7, GTP-binding nuclear protein ran, HREV3 fusion (EC 2.7.7.7)	protein	212	31% helix, 30% strand	Q9UI95, F5H018, O60673

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	111	0.40	0.75	19	empty

Compared structures

6NIF · crystal structure of human REV7-RAN complex · the same entry in another collection · chain A against A, TM-score 1.00
Q9UI95 · AlphaFold monomer V2.0 prediction for mitotic spindle assembly checkpoint protein MAD2B… · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UI95
Every structure of UniProt F5H018
Every structure of UniProt O60673
Elsewhere: RCSB PDB 6NIF · PDBe 6NIF · UniProt Q9UI95 · UniProt F5H018 · UniProt O60673

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