MolNFT v1 · #158027 · protein
Structure of the transmembrane domain of the death receptor 5 - dimer of trimer
6NHW · Tumor necrosis factor receptor superfamily member 10B: “Structure of the transmembrane domain of the death receptor 5 - dimer of trimer”. Solution nmr, 1 pocket (best druggability 0.66). MolNFT v1 #158027 on GenesisL1: 3D structure…
- PDB
- 6NHW
- Type
- protein
- Length
- 216 residues
- Chains
- 6
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tumor necrosis factor receptor superfamily member 10B
- UniProt
- O14763
- Pockets
- 1 · best druggability 0.66
Structure
solution nmr · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | Tumor necrosis factor receptor superfamily member 10B | protein | 36 | 72% helix, 0% strand | O14763 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 654 | 0.66 | 0.75 | 46 | empty |
Interfaces
9 interfaces between chains.
- A–D · 381 Ų buried · 0 hydrogen bonds · protein-protein
- D–F · 253 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 227 Ų buried · 0 hydrogen bonds · protein-protein
- E–F · 212 Ų buried · 0 hydrogen bonds · protein-protein
- A–C · 207 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6NHW · Structure of the transmembrane domain of the Death Receptor 5 - Dimer of Trimer · the same entry in another collection · chain C against C, TM-score 1.00
- O14763 · AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member… · a predicted model of the same protein · chain A against A, TM-score 0.51
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14763
- Elsewhere: RCSB PDB 6NHW · PDBe 6NHW · UniProt O14763
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