UniProt O14763
Tumor necrosis factor receptor superfamily member 10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (UniProt O14763): 20 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14763
- Protein
- Tumor necrosis factor receptor superfamily member 10B
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 5 · 0 records with a druggable one
Structures
21 records of O14763 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D0G | Crystal structure of death receptor 5 (DR5) bound to APO2L/TRAIL | x-ray diffraction | R, S, T | — | — |
| 1D0G | Crystal structure of death receptor 5 (DR5) bound to APO2L/TRAIL | x-ray diffraction | R, S, T | — | — |
| 1DU3 | Crystal structure of TRAIL-SDR5 | x-ray diffraction | A, B, C, G, H, I | — | — |
| 1DU3 | Crystal structure of trail-SDR5 | x-ray diffraction | A, B, C, G, H, I | — | — |
| 1ZA3 | The crystal structure of the YSd1 Fab bound to DR5 | x-ray diffraction | R, S | — | — |
| 1ZA3 | The crystal structure of the YSD1 Fab bound to DR5 | x-ray diffraction | R, S | — | — |
| 2H9G | Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5) | x-ray diffraction | R, S | — | — |
| 2H9G | Crystal structure of phage derived Fab BDF1 with human death receptor 5 (DR5) | x-ray diffraction | R, S | — | — |
| 3X3F | TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2 | x-ray diffraction | A | — | — |
| 3X3F | Trail-R2 extracellular region complexed to a Fab fragment from human agonist antibody KMTR2 | x-ray diffraction | A | — | — |
| 4I9X | Crystal structure of human cytomegalovirus glycoprotein UL141 targeting the death receptor TRAIL-R2 | x-ray diffraction | C, D | — | — |
| 4I9X | Crystal structure of human cytomegalovirus glycoprotein UL141 targeting the death receptor trail-R2 | x-ray diffraction | C, D | — | — |
| 4N90 | Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody | x-ray diffraction | R, S, T | — | — |
| 4N90 | Crystal structure of ternary complex of trail, DR5, and Fab fragment from a DR5 agonist antibody | x-ray diffraction | R, S, T | — | — |
| 4OD2 | Crystal structure of the Fab fragment of an anti-DR5 antibody bound to DR5 | x-ray diffraction | S | — | — |
| 4OD2 | Crystal structure of the Fab fragment of an anti-DR5 antibody bound to DR5 | x-ray diffraction | S | — | — |
| 6NHW | Structure of the transmembrane domain of the death receptor 5 - dimer of trimer | solution nmr | A, B, C, D, E, F | — | — |
| 6NHY | Structure of the transmembrane domain of the death receptor 5 mutant (G217Y) - trimer only | solution nmr | A, B, C | — | — |
| 6T3J | Dual Epitope Targeting by Anti-DR5 Antibodies | x-ray diffraction | E, J | — | 4 (best 0.45) |
| 6T3J | Dual epitope targeting by anti-DR5 antibodies | x-ray diffraction | E, J | — | — |
| O14763 | AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 10B (O14763) | predicted | A | — | 1 (best 0.31) |
Experiment against prediction
- 4N90 chain R against the predicted model O14763: TM-score 0.98, RMSD 0.57 Å
- 4N90 chain R against the predicted model O14763: TM-score 0.98, RMSD 0.57 Å
- 1DU3 chain A against the predicted model O14763: TM-score 0.98, RMSD 0.56 Å
- 1DU3 chain A against the predicted model O14763: TM-score 0.98, RMSD 0.56 Å
- 1DU3 chain G against the predicted model O14763: TM-score 0.97, RMSD 0.70 Å
- 1DU3 chain G against the predicted model O14763: TM-score 0.97, RMSD 0.70 Å
- 4N90 chain T against the predicted model O14763: TM-score 0.97, RMSD 0.69 Å
- 4N90 chain T against the predicted model O14763: TM-score 0.97, RMSD 0.69 Å
- 3X3F chain A against the predicted model O14763: TM-score 0.96, RMSD 0.61 Å
- 3X3F chain A against the predicted model O14763: TM-score 0.96, RMSD 0.61 Å
Elsewhere
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