MolNFT v1 · #1580 · protein

Mutl complexed with ADP

1B62 · Protein (mutl): “Mutl complexed with ADP”. X-ray diffraction, 2 ligands (ADP, MG), 2 pockets (best druggability 0.74). MolNFT v1 #1580 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1B62
Type: protein
Length: 331 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (mutl)
UniProt: P23367
Ligands: ADP, MG
Pockets: 2 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (mutl)	protein	331	37% helix, 26% strand	P23367

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	515	0.74	0.82	55	MG, ADP
2	222	0.54	0.78	44	empty

Compared structures

1B62 · Mutl complexed with ADP · the same entry in another collection · chain A against A, TM-score 1.00
P23367 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (P23367) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23367
Elsewhere: RCSB PDB 1B62 · PDBe 1B62 · UniProt P23367

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