UniProt P23367
DNA mismatch repair protein MutL (P23367)
DNA mismatch repair protein MutL (UniProt P23367): 16 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P23367
- Protein
- DNA mismatch repair protein MutL
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 31 · 3 records with a druggable one
Structures
17 records of P23367 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B62 | Mutl complexed with ADP | x-ray diffraction | A | — | — |
| 1B62 | Mutl complexed with ADP | x-ray diffraction | A | — | — |
| 1B63 | Mutl complexed with adpnp | x-ray diffraction | A | — | — |
| 1B63 | Mutl complexed with adpnp | x-ray diffraction | A | — | — |
| 1BKN | Crystal structure of an N-terminal 40KD fragment of E. COLI DNA mismatch repair protein mutl | x-ray diffraction | A, B | — | — |
| 1BKN | Crystal structure of an N-terminal 40KD fragment of E. COLI DNA mismatch repair protein mutl | x-ray diffraction | A, B | — | — |
| 1X9Z | Crystal structure of the MutL C-terminal domain | x-ray diffraction | A, B | — | — |
| 1X9Z | Crystal structure of the mutl C-terminal domain | x-ray diffraction | A, B | — | — |
| 5AKB | Muts in complex with the N-terminal domain of mutl - crystal form 1 | x-ray diffraction | C, D, F | — | — |
| 5AKC | MutS in complex with the N-terminal domain of MutL - crystal form 2 | x-ray diffraction | C, D, G, H, K, L | — | 17 (best 0.80) |
| 5AKC | Muts in complex with the N-terminal domain of mutl - crystal form 2 | x-ray diffraction | C, D, G, H, K, L | — | — |
| 5AKD | Muts in complex with the N-terminal domain of mutl - crystal form 3 | x-ray diffraction | C, D, G, H, K, L | — | — |
| 7AIB | Muts-mutl in clamp state | electron microscopy | C | — | — |
| 7AIC | MutS-MutL in clamp state (kinked clamp domain) | electron microscopy | C | — | 9 (best 0.82) |
| 7AIC | Muts-mutl in clamp state (kinked clamp domain) | electron microscopy | C | — | — |
| 7P8V | The structure of E. COLI mutl bound to a 3' resected DNA end | electron microscopy | A, B | ANP, MG | — |
| P23367 | AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (P23367) | predicted | A | — | 5 (best 0.73) |
Ligands
Experiment against prediction
- 1B63 chain A against the predicted model P23367: TM-score 0.99, RMSD 0.31 Å
- 1B63 chain A against the predicted model P23367: TM-score 0.99, RMSD 0.31 Å
- 1B62 chain A against the predicted model P23367: TM-score 0.99, RMSD 0.53 Å
- 1B62 chain A against the predicted model P23367: TM-score 0.99, RMSD 0.53 Å
- 7P8V chain A against the predicted model P23367: TM-score 0.98, RMSD 1.07 Å
- 1X9Z chain A against the predicted model P23367: TM-score 0.96, RMSD 1.25 Å
- 1X9Z chain A against the predicted model P23367: TM-score 0.96, RMSD 1.25 Å
- 1X9Z chain B against the predicted model P23367: TM-score 0.95, RMSD 1.49 Å
- 1X9Z chain B against the predicted model P23367: TM-score 0.95, RMSD 1.49 Å
- 7AIC chain C against the predicted model P23367: TM-score 0.93, RMSD 1.69 Å
Elsewhere
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