MolNFT v1 · #157853 · protein
The dimerization domain of human sfpq in space group C2221
6NCQ · Splicing factor, proline- and glutamine-rich: “The dimerization domain of human sfpq in space group C2221”. X-ray diffraction, 2 pockets (best druggability 0.38). MolNFT v1 #157853 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6NCQ
- Type
- protein
- Length
- 257 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Splicing factor, proline- and glutamine-rich
- UniProt
- P23246
- Pockets
- 2 · best druggability 0.38
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Splicing factor, proline- and glutamine-rich | protein | 257 | 42% helix, 19% strand | P23246 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 133 | 0.38 | 0.73 | 21 | empty |
| 2 | 94 | 0.38 | 0.76 | 19 | empty |
Compared structures
- 6NCQ · The dimerization domain of human SFPQ in space group C2221 · the same entry in another collection · chain A against A, TM-score 1.00
- P23246 · AlphaFold monomer V2.0 prediction for splicing factor, proline- and glutamine-rich… · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23246
- Elsewhere: RCSB PDB 6NCQ · PDBe 6NCQ · UniProt P23246
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