MolNFT v1 · #157650 · DNA
KRAS G-quadruplex G16T mutant.
6N65: “KRAS G-quadruplex G16T mutant.”. X-ray diffraction, 1 ligand (K), 1 pocket (best druggability 0.42). MolNFT v1 #157650 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6N65
- Type
- DNA
- Length
- 44 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- KRAS G-quadruplex G16T mutant
- Ligands
- K
- Pockets
- 1 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | KRAS G-quadruplex G16T mutant | dna | 22 | — | — |
Ligands and binding sites
- K · Potassium ion · metal · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.42 | 0.81 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 711 Ų buried · 20 hydrogen bonds · nucleic-nucleic
Compared structures
- 6N65 · KRAS G-quadruplex G16T mutant. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6N65 · PDBe 6N65
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