Research workbench

KRAS G-quadruplex G16T mutant.

Analyse KRAS G-quadruplex G16T mutant. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6N65
Type: DNA
Length: 44 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: KRAS G-quadruplex G16T mutant
Ligands: K
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	KRAS G-quadruplex G16T mutant	dna	22	—	—

Ligands and binding sites

K · Potassium ion · metal · 5 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.42	0.81	12	empty

Interfaces

1 interface between chains.

A–B · 711 Å² buried · 20 hydrogen bonds · nucleic-nucleic

Compared structures

6N65 · KRAS G-quadruplex G16T mutant. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6N65 · PDBe 6N65

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.