MolNFT v1 · #157579 · protein
Crystal structure of MMPL3 from mycobacterium smegmatis
6N40 · Membrane protein, mmpl family protein: “Crystal structure of MMPL3 from mycobacterium smegmatis”. X-ray diffraction, 6 pockets (best druggability 0.83). MolNFT v1 #157579 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6N40
- Type
- protein
- Length
- 726 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Membrane protein, mmpl family protein
- UniProt
- A0QP27
- Pockets
- 6 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Membrane protein, mmpl family protein | protein | 726 | 64% helix, 6% strand | A0QP27 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1030 | 0.83 | 0.83 | 68 | empty |
| 2 | 234 | 0.65 | 0.83 | 33 | empty |
| 3 | 131 | 0.59 | 0.85 | 18 | empty |
| 4 | 159 | 0.46 | 0.76 | 37 | empty |
| 5 | 91 | 0.39 | 0.76 | 18 | empty |
Compared structures
- 6N40 · Crystal structure of MmpL3 from Mycobacterium smegmatis · the same entry in another collection · chain A against A, TM-score 1.00
- A0QP27 · AlphaFold monomer V2.0 prediction for trehalose monomycolate exporter MMPL3 (A0QP27) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0QP27
- Elsewhere: RCSB PDB 6N40 · PDBe 6N40 · UniProt A0QP27
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