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UniProt A0QP27

Membrane protein, MmpL family protein (A0QP27)

Membrane protein, MmpL family protein (UniProt A0QP27): 6 experimental structures on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0QP27
Protein
Membrane protein, MmpL family protein
Experimental structures
6
Predicted models
0
Ligands
2
Pockets
6 · 1 record with a druggable one

Structures

6 records of A0QP27 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6N40Crystal structure of MMPL3 from mycobacterium smegmatisx-ray diffractionA——
6OR2MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolaminex-ray diffractionAL9Q6 (best 0.80)
6OR2MMPL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolaminex-ray diffractionAL9Q—
7K8CCryoem structure of a trehalose monomycolate transporter in lipid nanodiscselectron microscopyA——
7WNXCryo-EM structure of mycobacterium smegmatis MMPL3 complexed with ST004 in lipid nanodiscselectron microscopyA1I2—
A0QP27AlphaFold monomer V2.0 prediction for trehalose monomycolate exporter MMPL3 (A0QP27)———

Ligands

  • L9Q · (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate · in 2 records
  • 1I2 · N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl) phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide · in 1 record

Elsewhere

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