MolNFT v1 · #157245 · protein
Crystal structure of human pim-1 kinase in complex with a quinazolinone-pyrrolodihydropyrrolone inhibitor
6MT0: “Crystal structure of human pim-1 kinase in complex with a quinazolinone-pyrrolodihydropyrrolone inhibitor”. X-ray diffraction, 1 ligand (JYG). MolNFT v1 #157245 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MT0
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P11309
- Ligands
- JYG
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 273 | — | P11309 |
Ligands and binding sites
- JYG · 3-(1-methylcyclopropyl)-2-[(1-methylcyclopropyl)amino]-8-[(6R)-6-methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4-b]pyrrol-2-yl]quinazolin-4(3H)-one · ligand · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MT0 · Crystal structure of human Pim-1 kinase in complex with a quinazoli… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11309
- Elsewhere: RCSB PDB 6MT0 · PDBe 6MT0 · UniProt P11309
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