MolNFT v1 · #15723 · protein

Crystal structure of NADH-cytochrome B5 reductase from pig liver at 2.4 ångströms resolution

1NDH: “Crystal structure of NADH-cytochrome B5 reductase from pig liver at 2.4 ångströms resolution”. X-ray diffraction, 1 ligand (FAD), 3 pockets (best druggability 0.57). MolNFT v1 #15723 on GenesisL1: 3D structure, binding sites and…

PDB: 1NDH
Type: protein
Length: 270 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytochrome B5 reductase
EC: 1.6.2.2
UniProt: P83686
Ligands: FAD
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytochrome B5 reductase (EC 1.6.2.2)	protein	270	21% helix, 34% strand	P83686

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	284	0.57	0.77	42	FAD
2	107	0.44	0.78	20	empty
3	61	0.40	0.80	20	empty

Compared structures

1NDH · Crystal structure of NADH-cytochrome B5 reductase from pig liver at 2.4 ångströms… · the same entry in another collection · chain A against A, TM-score 1.00
P83686 · AlphaFold monomer V2.0 prediction for NADH-cytochrome B5 reductase 3 (P83686) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P83686
Elsewhere: RCSB PDB 1NDH · PDBe 1NDH · UniProt P83686

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