MolNFT v1 · #157170 · protein

Crystal structure of GTPase domain of human septin 12 in complex with GDP

6MQK: “Crystal structure of GTPase domain of human septin 12 in complex with GDP”. X-ray diffraction, 2 ligands (GDP, MG). MolNFT v1 #157170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MQK
Type: protein
Length: 1,055 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q8IYM1
Ligands: GDP, MG

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	261	—	Q8IYM1
B	—	protein	265	—	Q8IYM1
C	—	protein	262	—	Q8IYM1
D	—	protein	267	—	Q8IYM1

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · 4 copies · chains A, D, B, C
MG · Magnesium ion · metal · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6MQK · Crystal Structure of GTPase Domain of Human Septin 12 in complex with GDP · the same entry in another collection · chain D against D, TM-score 1.00
Q8IYM1 · AlphaFold monomer V2.0 prediction for septin-12 (Q8IYM1) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IYM1
Elsewhere: RCSB PDB 6MQK · PDBe 6MQK · UniProt Q8IYM1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.