MolNFT v1 · #157069 · protein

Hadza microbial sialidase HZ136

6MNJ: “Hadza microbial sialidase HZ136”. X-ray diffraction, 8 pockets (best druggability 0.69). MolNFT v1 #157069 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MNJ
Type: protein
Length: 1,022 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HZ136
Pockets: 8 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	HZ136	protein	511	5% helix, 44% strand	—

Pockets

8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	327	0.69	0.83	38	empty
2	301	0.65	0.81	39	empty
3	355	0.59	0.76	60	empty
4	302	0.57	0.77	48	empty
5	140	0.56	0.83	22	empty

Interfaces

1 interface between chains.

A–B · 1581 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

6MNJ · Hadza microbial sialidase Hz136 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6MNJ · PDBe 6MNJ

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