Research workbench
Hadza microbial sialidase HZ136
Analyse Hadza microbial sialidase HZ136 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6MNJ
- Type
- protein
- Length
- 1,022 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HZ136
- Pockets
- 8 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | HZ136 | protein | 511 | 5% helix, 44% strand | — |
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 327 | 0.69 | 0.83 | 38 | empty |
| 2 | 301 | 0.65 | 0.81 | 39 | empty |
| 3 | 355 | 0.59 | 0.76 | 60 | empty |
| 4 | 302 | 0.57 | 0.77 | 48 | empty |
| 5 | 140 | 0.56 | 0.83 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1581 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 6MNJ · Hadza microbial sialidase Hz136 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6MNJ · PDBe 6MNJ
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