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MolNFT v1 · #156912 · protein

Wwe domain of human HUWE1

6MIW · E3 ubiquitin-protein ligase HUWE1: “Wwe domain of human HUWE1”. X-ray diffraction, 1 ligand (UNX). MolNFT v1 #156912 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6MIW
Type
protein
Length
69 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
E3 ubiquitin-protein ligase HUWE1
EC
2.3.2.26
UniProt
Q7Z6Z7
Ligands
UNX

Structure

x-ray diffraction · 1 distinct chain · 17% helix, 48% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AE3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26)protein6917% helix, 48% strandQ7Z6Z7

Ligands and binding sites

  • UNX · Unknown atom or ion · ion · 10 copies · chains A
  • MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6MIW · WWE domain of human HUWE1 · the same entry in another collection · chain A against A, TM-score 1.00

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