MolNFT v1 · #156790 · protein
Mutated uronate dehydrogenase
6MFH: “Mutated uronate dehydrogenase”. X-ray diffraction, 1 ligand (PO4), 3 pockets (best druggability 0.63). MolNFT v1 #156790 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MFH
- Type
- protein
- Length
- 275 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mutated uronate dehydrogenase
- EC
- 1.-.-.-
- Ligands
- PO4
- Pockets
- 3 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mutated uronate dehydrogenase (EC 1.-.-.-) | protein | 275 | 43% helix, 17% strand | — |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A
- DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 362 | 0.63 | 0.78 | 48 | DTT, PO4 |
| 2 | 84 | 0.42 | 0.79 | 22 | empty |
| 3 | 55 | 0.27 | 0.74 | 15 | empty |
Compared structures
- 6MFH · Mutated Uronate Dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6MFH · PDBe 6MFH
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