MolNFT v1 · #156688 · protein

Crystal structure of ppra dimer from deinococcus deserti

6MC8 · DNA repair protein ppra: “Crystal structure of ppra dimer from deinococcus deserti”. X-ray diffraction, 5 pockets (best druggability 0.60). MolNFT v1 #156688 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MC8
Type: protein
Length: 549 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair protein ppra
UniProt: C1D318
Pockets: 5 · best druggability 0.60

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA repair protein ppra	protein	275	50% helix, 19% strand	C1D318
B	DNA repair protein ppra	protein	274	49% helix, 18% strand	C1D318

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	238	0.60	0.80	44	empty
2	82	0.50	0.83	19	empty
3	144	0.48	0.78	27	empty
4	114	0.43	0.78	19	empty
5	51	0.27	0.75	16	empty

Interfaces

1 interface between chains.

A–B · 799 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

6MC8 · Crystal structure of PprA dimer from Deinococcus deserti · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C1D318
Elsewhere: RCSB PDB 6MC8 · PDBe 6MC8 · UniProt C1D318

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