MolNFT v1 · #156648 · protein
Crystal structure of N-myristoyl transferase (nmt) G386E mutant from plasmodium vivax in complex with inhibitor imp-1002
6MB0: “Crystal structure of N-myristoyl transferase (nmt) G386E mutant from plasmodium vivax in complex with…”. X-ray diffraction, 4 ligands (YNC, JCY, CL). MolNFT v1 #156648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MB0
- Type
- protein
- Length
- 1,144 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A1G4HIY1
- Ligands
- YNC, JCY, CL, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 385 | — | A0A1G4HIY1 |
| C | — | protein | 374 | — | A0A1G4HIY1 |
Ligands and binding sites
- YNC · Tetradec-13-ynoic acid - coa thioester · ligand · 3 copies · chains A, B, C
- JCY · 1-(5-{4-fluoro-2-[2-(1,3,5-trimethyl-1H-pyrazol-4-yl) ethoxy]phenyl}-1-methyl-1H-indazol-3-yl)-N,N-dimethylmethanamine · ligand · 3 copies · chains A, B, C
- CL · Chloride ion · ion · 3 copies · chains A, B, C
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MB0 · Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1G4HIY1
- Elsewhere: RCSB PDB 6MB0 · PDBe 6MB0 · UniProt A0A1G4HIY1
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