GL1X · GenesisL1 explorer

MolNFT v1 · #156599 · protein

Pseudomonas serine-carboxyl proteinase (sedolisin) complexed with the inhibitor chymostatin

6M9D: “Pseudomonas serine-carboxyl proteinase (sedolisin) complexed with the inhibitor chymostatin”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.37). MolNFT v1 #156599 on GenesisL1: 3D structure, binding sites and…

PDB
6M9D
Type
protein
Length
371 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Sedolisin; Chymostatin a
EC
3.4.21.100
UniProt
P42790
Ligands
CA
Pockets
1 · best druggability 0.37

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 27% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASedolisin (EC 3.4.21.100)protein36833% helix, 27% strandP42790
BChymostatin aprotein30% helix, 33% strand—

Ligands and binding sites

  • CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11160.370.7425empty

Interfaces

1 interface between chains.

  • A–B · 402 Ų buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified, 1 disulfide (nonstandard, disulfide).

Compared structures

  • 6M9D · PSEUDOMONAS SERINE-CARBOXYL PROTEINASE (SEDOLISIN) COMPLEXED WITH THE INHIBITOR… · the same entry in another collection · chain A against A, TM-score 1.00
  • P42790 · AlphaFold monomer V2.0 prediction for pseudomonalisin (P42790) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.