MolNFT v1 · #156292 · protein

Tetrameric structure of ZMCRY1A phr domain

6LZ7 · Cryptochrome-1: “Tetrameric structure of ZMCRY1A phr domain”. X-ray diffraction, 1 ligand (FAD), 9 pockets (best druggability 0.82). MolNFT v1 #156292 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6LZ7
Type: protein
Length: 492 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cryptochrome-1
UniProt: A0A1D6HB66
Ligands: FAD
Pockets: 9 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cryptochrome-1	protein	492	47% helix, 5% strand	A0A1D6HB66

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	661	0.82	0.86	51	FAD
2	103	0.74	0.95	20	empty
3	60	0.72	0.97	19	empty
4	213	0.59	0.80	21	empty
5	94	0.43	0.78	16	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6LZ7 · Tetrameric structure of ZmCRY1a PHR domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1D6HB66
Elsewhere: RCSB PDB 6LZ7 · PDBe 6LZ7 · UniProt A0A1D6HB66

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