MolNFT v1 · #156175 · protein
Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative
6LVL: “Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative”. X-ray diffraction, 2 ligands (EVL, SO4). MolNFT v1 #156175 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LVL
- Type
- protein
- Length
- 574 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P21802
- Ligands
- EVL, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 288 | — | P21802 |
| B | — | protein | 286 | — | P21802 |
Ligands and binding sites
- EVL · N-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LVL · Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative · the same entry in another collection · chain A against A, TM-score 1.00
- P21802 · AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 2 (P21802) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21802
- Elsewhere: RCSB PDB 6LVL · PDBe 6LVL · UniProt P21802
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