MolNFT v1 · #155770 · protein

Crystal structure of thsb

6LHY · DUF1863 domain-containing protein: “Crystal structure of thsb”. X-ray diffraction, 2 pockets (best druggability 0.41). MolNFT v1 #155770 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6LHY
Type: protein
Length: 350 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DUF1863 domain-containing protein
UniProt: J8G8J6
Pockets: 2 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DUF1863 domain-containing protein	protein	177	34% helix, 24% strand	J8G8J6
B	DUF1863 domain-containing protein	protein	173	33% helix, 25% strand	J8G8J6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	123	0.41	0.76	22	empty
2	62	0.37	0.78	14	empty

Interfaces

1 interface between chains.

A–B · 804 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

6LHY · Crystal structure of ThsB · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt J8G8J6
Elsewhere: RCSB PDB 6LHY · PDBe 6LHY · UniProt J8G8J6

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