MolNFT v1 · #155371 · protein
ARF5 AUX/IAA17 complex
6L5K · Auxin response factor 5: “ARF5 AUX/IAA17 complex”. X-ray diffraction, 3 pockets (best druggability 0.52). MolNFT v1 #155371 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6L5K
- Type
- protein
- Length
- 173 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Auxin response factor 5; Auxin-responsive protein IAA17
- UniProt
- P93024, P93830
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Auxin response factor 5 | protein | 92 | 29% helix, 26% strand | P93024 |
| B | Auxin-responsive protein IAA17 | protein | 81 | 31% helix, 31% strand | P93830 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.52 | 0.84 | 20 | empty |
| 2 | 79 | 0.40 | 0.79 | 18 | empty |
| 3 | 72 | 0.35 | 0.77 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 638 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 6L5K · ARF5 Aux/IAA17 Complex · the same entry in another collection · chain A against A, TM-score 1.00
- P93024 · AlphaFold monomer V2.0 prediction for auxin response factor 5 (P93024) · a predicted model of the same protein · chain A against A, TM-score 0.94
- P93830 · AlphaFold monomer V2.0 prediction for auxin-responsive protein IAA17 (P93830) · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P93024
- Every structure of UniProt P93830
- Elsewhere: RCSB PDB 6L5K · PDBe 6L5K · UniProt P93024 · UniProt P93830
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