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ARF5 AUX/IAA17 complex

Analyse ARF5 AUX/IAA17 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6L5K
Type
protein
Length
173 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Auxin response factor 5; Auxin-responsive protein IAA17
UniProt
P93024, P93830
Pockets
3 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 30% helix, 28% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAuxin response factor 5protein9229% helix, 26% strandP93024
BAuxin-responsive protein IAA17protein8131% helix, 31% strandP93830

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1800.520.8420empty
2790.400.7918empty
3720.350.7716empty

Interfaces

1 interface between chains.

  • A–B · 638 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

  • 6L5K · ARF5 Aux/IAA17 Complex · the same entry in another collection · chain A against A, TM-score 1.00
  • P93024 · AlphaFold monomer V2.0 prediction for auxin response factor 5 (P93024) · a predicted model of the same protein · chain A against A, TM-score 0.94
  • P93830 · AlphaFold monomer V2.0 prediction for auxin-responsive protein IAA17 (P93830) · a predicted model of the same protein · chain B against A, TM-score 0.88

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