MolNFT v1 · #155053 · protein

The solution structure of human ORC6

6KVG · Origin recognition complex subunit 6: “The solution structure of human ORC6”. Solution nmr, 2 pockets (best druggability 0.56). MolNFT v1 #155053 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6KVG
Type: protein
Length: 256 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Origin recognition complex subunit 6
UniProt: Q9Y5N6
Pockets: 2 · best druggability 0.56

Structure

solution nmr · 1 distinct chain · 55% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Origin recognition complex subunit 6	protein	256	55% helix, 0% strand	Q9Y5N6

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	269	0.56	0.77	34	empty
2	133	0.39	0.73	19	empty

Compared structures

6KVG · The solution structure of human Orc6 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y5N6 · AlphaFold monomer V2.0 prediction for origin recognition complex subunit 6 (Q9Y5N6) · a predicted model of the same protein · chain A against A, TM-score 0.51

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y5N6
Elsewhere: RCSB PDB 6KVG · PDBe 6KVG · UniProt Q9Y5N6

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