UniProt Q9Y5N6
Origin recognition complex subunit 6 (Q9Y5N6)
Origin recognition complex subunit 6 (UniProt Q9Y5N6): 6 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5N6
- Protein
- Origin recognition complex subunit 6
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 9 · 3 records with a druggable one
Structures
7 records of Q9Y5N6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3M03 | Crystal structure of human Orc6 fragment | x-ray diffraction | A, B, C | — | — |
| 3M03 | Crystal structure of human ORC6 fragment | x-ray diffraction | A, B, C | — | — |
| 6KVG | The solution structure of human Orc6 | solution nmr | A | — | 2 (best 0.56) |
| 6KVG | The solution structure of human ORC6 | solution nmr | A | — | — |
| 8S0B | H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex | electron microscopy | F | — | 2 (best 0.84) |
| 8S0D | H. sapiens MCM bound to double stranded DNA and ORC1-6 | electron microscopy | F | — | 3 (best 0.84) |
| Q9Y5N6 | AlphaFold monomer V2.0 prediction for origin recognition complex subunit 6 (Q9Y5N6) | predicted | A | — | 2 (best 0.40) |
Experiment against prediction
- 3M03 chain B against the predicted model Q9Y5N6: TM-score 0.96, RMSD 0.79 Å
- 3M03 chain B against the predicted model Q9Y5N6: TM-score 0.96, RMSD 0.79 Å
- 3M03 chain A against the predicted model Q9Y5N6: TM-score 0.95, RMSD 0.95 Å
- 3M03 chain A against the predicted model Q9Y5N6: TM-score 0.95, RMSD 0.95 Å
- 3M03 chain C against the predicted model Q9Y5N6: TM-score 0.95, RMSD 1.03 Å
- 3M03 chain C against the predicted model Q9Y5N6: TM-score 0.95, RMSD 1.03 Å
- 8S0D chain F against the predicted model Q9Y5N6: TM-score 0.70, RMSD 3.28 Å
- 8S0B chain F against the predicted model Q9Y5N6: TM-score 0.70, RMSD 3.30 Å
- 6KVG chain A against the predicted model Q9Y5N6: TM-score 0.51, RMSD 4.65 Å
- 6KVG chain A against the predicted model Q9Y5N6: TM-score 0.51, RMSD 4.65 Å
Elsewhere
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