MolNFT v1 · #15459 · protein

NMR structures of the zinc finger domain of human DNA polymerase-alpha

1N5G · 38-mer of DNA polymerase alpha catalytic subunit: “NMR structures of the zinc finger domain of human DNA polymerase-alpha”. Solution nmr, 1 pocket (best druggability 0.33). MolNFT v1 #15459 on GenesisL1: 3D structure, binding sites…

PDB: 1N5G
Type: protein
Length: 38 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 38-mer of DNA polymerase alpha catalytic subunit
EC: 2.7.7.7
UniProt: P09884
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 50% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	38-mer of DNA polymerase alpha catalytic subunit (EC 2.7.7.7)	protein	38	50% helix, 0% strand	P09884

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.33	0.77	15	empty

Compared structures

1N5G · NMR Structures of the Zinc Finger Domain of Human DNA Polymerase-alpha · the same entry in another collection · chain A against A, TM-score 1.00
P09884 · AlphaFold monomer V2.0 prediction for DNA polymerase alpha catalytic subunit (P09884) · a predicted model of the same protein · chain A against A, TM-score 0.48

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09884
Elsewhere: RCSB PDB 1N5G · PDBe 1N5G · UniProt P09884

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