MolNFT v1 · #154494 · protein

Solution structure of the znf-ubp domain of USP20/VDU2

6KCZ · Ubiquitin carboxyl-terminal hydrolase 20: “Solution structure of the znf-ubp domain of USP20/VDU2”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.49). MolNFT v1 #154494 on GenesisL1: 3D structure, binding sites and…

PDB: 6KCZ
Type: protein
Length: 99 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin carboxyl-terminal hydrolase 20
EC: 3.4.19.12
UniProt: Q9Y2K6
Ligands: ZN
Pockets: 1 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 15% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12)	protein	99	15% helix, 16% strand	Q9Y2K6

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.49	0.79	19	empty

Compared structures

6KCZ · Solution structure of the ZnF-UBP domain of USP20/VDU2 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y2K6 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 20 (Q9Y2K6) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y2K6
Elsewhere: RCSB PDB 6KCZ · PDBe 6KCZ · UniProt Q9Y2K6

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