MolNFT v1 · #154387 · protein
Monomeric human atm (ataxia telangiectasia mutated) kinase
6K9K · Serine-protein kinase atm: “Monomeric human atm (ataxia telangiectasia mutated) kinase”. Electron microscopy, 20 pockets (best druggability 0.90). MolNFT v1 #154387 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6K9K
- Type
- protein
- Length
- 2,501 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serine-protein kinase atm
- EC
- 2.7.11.1
- UniProt
- Q13315
- Pockets
- 20 · best druggability 0.90
Structure
electron microscopy · 1 distinct chain · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serine-protein kinase atm (EC 2.7.11.1) | protein | 2501 | 67% helix, 1% strand | Q13315 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1001 | 0.90 | 0.92 | 128 | empty |
| 2 | 551 | 0.88 | 0.94 | 86 | empty |
| 3 | 685 | 0.86 | 0.90 | 92 | empty |
| 4 | 749 | 0.85 | 0.88 | 90 | empty |
| 5 | 473 | 0.82 | 0.88 | 54 | empty |
Compared structures
- 6K9K · Monomeric human ATM (Ataxia telangiectasia mutated) kinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13315
- Elsewhere: RCSB PDB 6K9K · PDBe 6K9K · UniProt Q13315
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