MolNFT v1 · #154324 · protein

Crystal structure of human AFF4-thd domain

6K7P · AF4/FMR2 family member 4: “Crystal structure of human AFF4-thd domain”. X-ray diffraction, 1 pocket (best druggability 0.43). MolNFT v1 #154324 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6K7P
Type: protein
Length: 216 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: AF4/FMR2 family member 4
UniProt: Q9UHB7
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	AF4/FMR2 family member 4	protein	216	74% helix, 0% strand	Q9UHB7

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	90	0.43	0.79	18	empty

Compared structures

6K7P · Crystal structure of human AFF4-THD domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9UHB7 · AlphaFold monomer V2.0 prediction for AF4/FMR2 family member 4 (Q9UHB7) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UHB7
Elsewhere: RCSB PDB 6K7P · PDBe 6K7P · UniProt Q9UHB7

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