MolNFT v1 · #154194 · protein
Human galectin-14 with lactose
6K2Z · Placental protein 13-like: “Human galectin-14 with lactose”. X-ray diffraction, 3 ligands (GAL, BGC, GLC), 1 pocket (best druggability 0.67). MolNFT v1 #154194 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6K2Z
- Type
- protein
- Length
- 274 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Placental protein 13-like
- UniProt
- Q8TCE9
- Ligands
- GAL, BGC, GLC
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 2% helix, 58% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Placental protein 13-like | protein | 138 | 2% helix, 57% strand | Q8TCE9 |
| B | Placental protein 13-like | protein | 136 | 2% helix, 58% strand | Q8TCE9 |
Ligands and binding sites
- GAL · beta-D-galactopyranose · sugar · 2 copies · chains A, B
- BGC · beta-D-glucopyranose · sugar · chains B
- GLC · alpha-D-glucopyranose · sugar · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 302 | 0.67 | 0.81 | 36 | empty |
Interfaces
1 interface between chains.
- A–B · 1820 Ų buried · 39 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TCE9
- Elsewhere: RCSB PDB 6K2Z · PDBe 6K2Z · UniProt Q8TCE9
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