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MolNFT v1 · #153758 · protein + DNA + RNA

Crystal structure of corynebacterium diphtheriae CAS9 in complex with sgrna and target DNA

6JOO: “Crystal structure of corynebacterium diphtheriae CAS9 in complex with sgrna and target DNA”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #153758 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6JOO
Type
protein + DNA + RNA
Length
965 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A2T1BQ76, Q6NKI3
Ligands
ZN

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein834—A0A2T1BQ76, Q6NKI3
B—rna95——
D—dna8——
C—dna28——

Ligands and binding sites

  • ZN · Zinc ion · metal · chains A
  • EDO · 1,2-ethanediol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6JOO · Crystal structure of Corynebacterium diphtheriae Cas9 in complex with sgRNA and target DNA · the same entry in another collection · chain A against A, TM-score 1.00
  • Q6NKI3 · AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS9 (Q6NKI3) · a predicted model of the same protein · chain A against A, TM-score 0.98

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