MolNFT v1 · #15353 · protein
Crystal structure of the extra-cellular domains of human interleukin-6 receptor alpha chain
1N26 · Il-6 receptor alpha chain: “Crystal structure of the extra-cellular domains of human interleukin-6 receptor alpha chain”. X-ray diffraction, 6 ligands (CYS, NAG, BMA). MolNFT v1 #15353 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1N26
- Type
- protein
- Length
- 299 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Il-6 receptor alpha chain
- UniProt
- P08887
- Ligands
- CYS, NAG, BMA, MAN, NDG, SO4
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Il-6 receptor alpha chain | protein | 299 | 2% helix, 44% strand | P08887 |
Ligands and binding sites
- CYS · Cysteine · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A
- BMA · beta-D-mannopyranose · sugar
- MAN · alpha-D-mannopyranose · sugar
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · sugar · chains A
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 4 disulfide, 4 glycan, 1 covalent (disulfide, N-glycosylation, covalent ligand).
Compared structures
- 1N26 · Crystal Structure of the extra-cellular domains of Human Interleukin-6 Receptor alpha… · the same entry in another collection · chain A against A, TM-score 1.00
- P08887 · AlphaFold monomer V2.0 prediction for interleukin-6 receptor subunit alpha (P08887) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08887
- Elsewhere: RCSB PDB 1N26 · PDBe 1N26 · UniProt P08887
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