MolNFT v1 · #153486 · protein

Crystal structure of PA0833 periplasmic domain from pseudomonas aeruginosa reveals an unexpected enlarged peptidoglycan binding pocket

6JFW · PA0833-pd protein: “Crystal structure of PA0833 periplasmic domain from pseudomonas aeruginosa reveals an unexpected enlarged…”. X-ray diffraction, 6 pockets (best druggability 0.54). MolNFT v1 #153486 on GenesisL1: 3D structure…

PDB: 6JFW
Type: protein
Length: 564 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PA0833-pd protein
UniProt: Q9I5A7
Pockets: 6 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	PA0833-pd protein	protein	141	43% helix, 25% strand	Q9I5A7

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	269	0.54	0.76	27	empty
2	220	0.51	0.76	19	empty
3	205	0.51	0.77	29	empty
4	164	0.44	0.75	24	empty
5	95	0.39	0.77	23	empty

Interfaces

3 interfaces between chains.

C–D · 484 Å² buried · 2 hydrogen bonds · protein-protein
A–B · 454 Å² buried · 2 hydrogen bonds · protein-protein
B–C · 159 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

6JFW · Crystal structure of PA0833 periplasmic domain from Pseudomonas aeruginosa reveals an… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I5A7
Elsewhere: RCSB PDB 6JFW · PDBe 6JFW · UniProt Q9I5A7

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