MolNFT v1 · #153404 · protein

Crystal structure of N-acetyl mannosmaine kinase in complex with mannac from haemophilus influenzae

6JDC · N-acetylmannosamine kinase: “Crystal structure of N-acetyl mannosmaine kinase in complex with mannac from haemophilus influenzae”. X-ray diffraction, 2 ligands (BM3, ZN), 1 pocket (best druggability 0.77). MolNFT v1 #153404 on…

PDB: 6JDC
Type: protein
Length: 269 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: N-acetylmannosamine kinase
EC: 2.7.1.60
UniProt: Q4QP43
Ligands: BM3, ZN
Pockets: 1 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	N-acetylmannosamine kinase (EC 2.7.1.60)	protein	269	38% helix, 25% strand	Q4QP43

Ligands and binding sites

BM3 · 2-acetamido-2-deoxy-alpha-D-mannopyranose · ligand · chains A
ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	159	0.77	0.94	39	BM3

Compared structures

6JDC · Crystal structure of N-acetyl mannosmaine kinase in complex with ManNAc from Haemophilus… · the same entry in another collection · chain A against A, TM-score 1.00
Q4QP43 · AlphaFold monomer V2.0 prediction for N-acetylmannosamine kinase (Q4QP43) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4QP43
Elsewhere: RCSB PDB 6JDC · PDBe 6JDC · UniProt Q4QP43

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