MolNFT v1 · #153314 · protein

Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R356A in complex with glucose

6JAQ · ABC transporter, periplasmic substrate-binding protein: “Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R356A in complex with glucose”. X-ray diffraction, 1 ligand (GLC), 2 pockets (best druggability…

PDB: 6JAQ
Type: protein
Length: 403 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ABC transporter, periplasmic substrate-binding protein
UniProt: Q5SLD7
Ligands: GLC
Pockets: 2 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ABC transporter, periplasmic substrate-binding protein	protein	403	50% helix, 16% strand	Q5SLD7

Ligands and binding sites

GLC · alpha-D-glucopyranose · sugar · chains A
EDO · 1,2-ethanediol · additive · 2 copies · chains A
GOL · Glycerol · additive · 2 copies · chains A
CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	160	0.80	0.96	34	GLC
2	51	0.45	0.84	14	GOL

Compared structures

6JAQ · Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R356A in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SLD7
Elsewhere: RCSB PDB 6JAQ · PDBe 6JAQ · UniProt Q5SLD7

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