MolNFT v1 · #153190 · protein
Structure of kibra and LATS1 complex
6J68 · Protein kibra: “Structure of kibra and LATS1 complex”. X-ray diffraction. MolNFT v1 #153190 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6J68
- Type
- protein
- Length
- 276 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein kibra; Peptide from SERINE/THREONINE-protein kinase LATS1
- EC
- 2.7.11.1
- UniProt
- Q5SXA9, Q8BYR2
Structure
x-ray diffraction · 4 distinct chains · 36% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein kibra | protein | 123 | 38% helix, 23% strand | Q5SXA9 |
| B | Protein kibra | protein | 121 | 40% helix, 18% strand | Q5SXA9 |
| C | Peptide from SERINE/THREONINE-protein kinase LATS1 (EC 2.7.11.1) | protein | 19 | 16% helix, 0% strand | Q8BYR2 |
| D | Peptide from SERINE/THREONINE-protein kinase LATS1 (EC 2.7.11.1) | protein | 13 | 0% helix, 0% strand | Q8BYR2 |
Interfaces
3 interfaces between chains.
- A–C · 722 Ų buried · 7 hydrogen bonds · protein-protein
- B–D · 670 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 663 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 6J68 · Structure of KIBRA and LATS1 Complex · the same entry in another collection · chain D against D, TM-score 1.00
- Q5SXA9 · AlphaFold monomer V2.0 prediction for protein kibra (Q5SXA9) · a predicted model of the same protein · chain A against A, TM-score 0.59
- Q8BYR2 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase LATS1 (Q8BYR2) · a predicted model of the same protein · chain D against A, TM-score 0.35
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SXA9
- Every structure of UniProt Q8BYR2
- Elsewhere: RCSB PDB 6J68 · PDBe 6J68 · UniProt Q5SXA9 · UniProt Q8BYR2
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