UniProt Q8BYR2
Peptide from Serine/threonine-protein kinase LATS1 (Q8BYR2)
Peptide from Serine/threonine-protein kinase LATS1 (UniProt Q8BYR2), EC 2.7.11.1: 4 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8BYR2
- Protein
- Peptide from Serine/threonine-protein kinase LATS1
- EC
- 2.7.11.1
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
5 records of Q8BYR2 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5B6B | Complex of LATS1 and phosphomimetic MOB1b | x-ray diffraction | J, C, E, G, I, L, N, P | — | — |
| 5B6B | Complex of LATS1 and phosphomimetic MOB1B | x-ray diffraction | J, C, E, G, I, L, N, P | — | — |
| 6J68 | Structure of KIBRA and LATS1 Complex | x-ray diffraction | C, D | — | — |
| 6J68 | Structure of kibra and LATS1 complex | x-ray diffraction | C, D | — | — |
| Q8BYR2 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase LATS1 (Q8BYR2) | predicted | A | — | 8 (best 0.82) |
Experiment against prediction
- 5B6B chain I against the predicted model Q8BYR2: TM-score 0.87, RMSD 1.42 Å
- 5B6B chain I against the predicted model Q8BYR2: TM-score 0.87, RMSD 1.42 Å
- 5B6B chain P against the predicted model Q8BYR2: TM-score 0.87, RMSD 1.36 Å
- 5B6B chain P against the predicted model Q8BYR2: TM-score 0.87, RMSD 1.36 Å
- 5B6B chain N against the predicted model Q8BYR2: TM-score 0.85, RMSD 1.45 Å
- 5B6B chain N against the predicted model Q8BYR2: TM-score 0.85, RMSD 1.45 Å
- 5B6B chain C against the predicted model Q8BYR2: TM-score 0.84, RMSD 1.60 Å
- 5B6B chain C against the predicted model Q8BYR2: TM-score 0.84, RMSD 1.60 Å
- 5B6B chain J against the predicted model Q8BYR2: TM-score 0.83, RMSD 1.68 Å
- 5B6B chain J against the predicted model Q8BYR2: TM-score 0.83, RMSD 1.68 Å
Elsewhere
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