MolNFT v1 · #153086 · protein

Crystal structure of tyrosinase caddy PROTEIN(MELC1)WITH tyrosinase (MELC2)FROM streptomyces avermitilis in complex with zinc ion

6J2U · Tyrosinase co-factor protein: “Crystal structure of tyrosinase caddy PROTEIN(MELC1)WITH tyrosinase (MELC2)FROM streptomyces avermitilis in…”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.46). MolNFT v1 #153086 on…

PDB: 6J2U
Type: protein
Length: 345 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tyrosinase co-factor protein; Tyrosinase
UniProt: Q93HL1, Q93HL2
Ligands: ZN
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 2 distinct chains · 37% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrosinase co-factor protein	protein	72	17% helix, 46% strand	Q93HL1
B	Tyrosinase	protein	273	42% helix, 4% strand	Q93HL2

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.46	0.80	22	empty

Interfaces

1 interface between chains.

A–B · 1018 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

6J2U · Crystal structure of Tyrosinase caddy protein(MelC1)with Tyrosinase (MelC2)from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q93HL1
Every structure of UniProt Q93HL2
Elsewhere: RCSB PDB 6J2U · PDBe 6J2U · UniProt Q93HL1 · UniProt Q93HL2

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