MolNFT v1 · #152221 · protein
The archaeal methanocaldococcus infernus ELP3 with N-terminus deletion (1-46)
6IAZ · Histone acetyltransferase, ELP3 family: “The archaeal methanocaldococcus infernus ELP3 with N-terminus deletion (1-46)”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.80). MolNFT v1 #152221 on GenesisL1: 3D…
- PDB
- 6IAZ
- Type
- protein
- Length
- 426 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Histone acetyltransferase, ELP3 family
- EC
- 2.3.1.48
- UniProt
- D5VRB9
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone acetyltransferase, ELP3 family (EC 2.3.1.48) | protein | 426 | 36% helix, 24% strand | D5VRB9 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1137 | 0.80 | 0.81 | 94 | SO4 |
| 2 | 172 | 0.56 | 0.80 | 27 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6IAZ · The archaeal Methanocaldococcus infernus Elp3 with N-terminus deletion (1-46) · the same entry in another collection · chain A against A, TM-score 1.00
- D5VRB9 · AlphaFold monomer V2.0 prediction for tRNA URIDINE(34) acetyltransferase (D5VRB9) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D5VRB9
- Elsewhere: RCSB PDB 6IAZ · PDBe 6IAZ · UniProt D5VRB9
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