MolNFT v1 · #152163 · protein

NMR structure of the la module from human LARP4A

6I9B · La-related protein 4: “NMR structure of the la module from human LARP4A”. Solution nmr, 3 pockets (best druggability 0.70). MolNFT v1 #152163 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6I9B
Type: protein
Length: 177 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: La-related protein 4
UniProt: Q71RC2
Pockets: 3 · best druggability 0.70

Structure

solution nmr · 1 distinct chain · 36% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	La-related protein 4	protein	177	36% helix, 14% strand	Q71RC2

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.70	0.93	27	empty
2	251	0.47	0.73	37	empty
3	56	0.28	0.74	14	empty

Compared structures

6I9B · NMR structure of the La module from human LARP4A · the same entry in another collection · chain A against A, TM-score 1.00
Q71RC2 · AlphaFold monomer V2.0 prediction for la-related protein 4 (Q71RC2) · a predicted model of the same protein · chain A against A, TM-score 0.52

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q71RC2
Elsewhere: RCSB PDB 6I9B · PDBe 6I9B · UniProt Q71RC2

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