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NMR structure of the la module from human LARP4A

Analyse NMR structure of the la module from human LARP4A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6I9B
Type
protein
Length
177 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
La-related protein 4
UniProt
Q71RC2
Pockets
3 · best druggability 0.70

Structure

solution nmr · 1 distinct chain · 36% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALa-related protein 4protein17736% helix, 14% strandQ71RC2

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1940.700.9327empty
22510.470.7337empty
3560.280.7414empty

Compared structures

  • 6I9B · NMR structure of the La module from human LARP4A · the same entry in another collection · chain A against A, TM-score 1.00
  • Q71RC2 · AlphaFold monomer V2.0 prediction for la-related protein 4 (Q71RC2) · a predicted model of the same protein · chain A against A, TM-score 0.52

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