MolNFT v1 · #151771 · protein
Structure of the citryl-CoA lyase core module of chlorobium limicola ATP citrate lyase (space group P3121)
6HXN · ATP-citrate lyase alpha-subunit: “Structure of the citryl-CoA lyase core module of chlorobium limicola ATP citrate lyase (space group P3121)”. X-ray diffraction, 2 ligands (COA, SO4), 5 pockets (best druggability 0.61). MolNFT v1…
- PDB
- 6HXN
- Type
- protein
- Length
- 512 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATP-citrate lyase alpha-subunit
- UniProt
- Q9AJC4
- Ligands
- COA, SO4
- Pockets
- 5 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ATP-citrate lyase alpha-subunit | protein | 256 | 55% helix, 4% strand | Q9AJC4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 344 | 0.61 | 0.78 | 33 | SO4 |
| 2 | 326 | 0.60 | 0.78 | 33 | SO4 |
| 3 | 217 | 0.52 | 0.76 | 25 | empty |
| 4 | 192 | 0.48 | 0.75 | 25 | empty |
| 5 | 62 | 0.30 | 0.73 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 1532 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6HXN · Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9AJC4
- Elsewhere: RCSB PDB 6HXN · PDBe 6HXN · UniProt Q9AJC4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.