MolNFT v1 · #151416 · protein
A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor rxr-alpha
6HN6 · Retinoic acid receptor rxr-alpha: “A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor rxr-alpha”. X-ray diffraction, 1 ligand (CPS), 2 pockets (best druggability 0.58). MolNFT v1…
- PDB
- 6HN6
- Type
- protein
- Length
- 238 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Retinoic acid receptor rxr-alpha
- UniProt
- P19793
- Ligands
- CPS
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 68% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Retinoic acid receptor rxr-alpha | protein | 238 | 68% helix, 3% strand | P19793 |
Ligands and binding sites
- CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · ligand · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 287 | 0.58 | 0.78 | 27 | CPS |
| 2 | 66 | 0.32 | 0.74 | 12 | empty |
Compared structures
- 6HN6 · A revisited version of the apo structure of the ligand-binding domain of the human… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19793
- Elsewhere: RCSB PDB 6HN6 · PDBe 6HN6 · UniProt P19793
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