UniProt P19793
Retinoic acid receptor RXR-alpha (P19793)
Retinoic acid receptor RXR-alpha (UniProt P19793): 177 experimental structures on GenesisL1, 28 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P19793
- Protein
- Retinoic acid receptor RXR-alpha
- Experimental structures
- 177
- Predicted models
- 0
- Ligands
- 28
- Pockets
- 16 · 2 records with a druggable one
Structures
177 records of P19793 in the MolNFT archive: 177 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BY4 | Structure and mechanism of the homodimeric assembly of the rxr on DNA | x-ray diffraction | A, B, C, D | — | — |
| 1BY4 | Structure and mechanism of the homodimeric assembly of the rxr on DNA | x-ray diffraction | A, B, C, D | — | — |
| 1DSZ | Structure of the RXR/RAR DNA-binding domain heterodimer in complex with the retinoic acid response… | x-ray diffraction | B | — | — |
| 1DSZ | Structure of the RXR/RAR DNA-binding domain heterodimer in complex with the retinoic acid response… | x-ray diffraction | B | — | — |
| 1FBY | Crystal structure of the human rxr alpha ligand binding domain bound to 9-cis retinoic acid | x-ray diffraction | A, B | — | — |
| 1FBY | Crystal structure of the human rxr alpha ligand binding domain bound to 9-cis retinoic acid | x-ray diffraction | A, B | — | — |
| 1FM6 | The 2.1 ångström resolution crystal structure of the heterodimer of the human rxralpha and… | x-ray diffraction | A, U | — | — |
| 1FM6 | The 2.1 ångström resolution crystal structure of the heterodimer of the human rxralpha and… | x-ray diffraction | A, U | — | — |
| 1FM9 | The 2.1 ångström resolution crystal structure of the heterodimer of the human rxralpha and… | x-ray diffraction | A | — | — |
| 1FM9 | The 2.1 ångström resolution crystal structure of the heterodimer of the human rxralpha and… | x-ray diffraction | A | — | — |
| 1G1U | The 2.5 ångström resolution crystal structure of the rxralpha ligand binding domain in tetramer in… | x-ray diffraction | A, B, C, D | — | — |
| 1G1U | The 2.5 ångström resolution crystal structure of the rxralpha ligand binding domain in tetramer in… | x-ray diffraction | A, B, C, D | — | — |
| 1G5Y | The 2.0 ångström resolution crystal structure of the rxralpha ligand binding domain tetramer in the… | x-ray diffraction | A, B, C, D | — | — |
| 1G5Y | The 2.0 ångström resolution crystal structure of the rxralpha ligand binding domain tetramer in the… | x-ray diffraction | A, B, C, D | — | — |
| 1K74 | The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and… | x-ray diffraction | A | — | — |
| 1K74 | The 2.3 ångström resolution crystal structure of the heterodimer of the human ppargamma and… | x-ray diffraction | A | — | — |
| 1MV9 | Crystal Structure of the human RXR alpha ligand binding domain bound to the eicosanoid DHA (Docosa… | x-ray diffraction | A | — | — |
| 1MV9 | Crystal structure of the human rxr alpha ligand binding domain bound to the eicosanoid dha (docosa… | x-ray diffraction | A | — | — |
| 1MVC | Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist… | x-ray diffraction | A | — | — |
| 1MVC | Crystal structure of the human rxr alpha ligand binding domain bound to the synthetic agonist… | x-ray diffraction | A | — | — |
| 1MZN | CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING… | x-ray diffraction | A, C, E, G | — | — |
| 1MZN | Crystal structure at 1.9 angstroems resolution of the homodimer of human rxr alpha ligand binding… | x-ray diffraction | A, C, E, G | — | — |
| 1R0N | Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex | x-ray diffraction | A | — | — |
| 1R0N | Crystal structure of heterodimeric ecdsyone receptor DNA binding complex | x-ray diffraction | A | — | — |
| 1RDT | Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the… | x-ray diffraction | A | — | — |
| 1RDT | Crystal structure of a new rexinoid bound to the rxralpha ligand binding doamin in the… | x-ray diffraction | A | — | — |
| 1RXR | High resolution solution structure of the retinoid X receptor DNA binding domain, NMR, 20 structure | solution nmr | A | — | — |
| 1RXR | High resolution solution structure of the retinoid X receptor DNA binding domain, NMR, 20 structure | solution nmr | A | — | — |
| 1XLS | Crystal structure of the mouse CAR/RXR LBD heterodimer bound to TCPOBOP and 9cRA and a TIF2 peptide… | x-ray diffraction | A, B, C, D | — | — |
| 1XLS | Crystal structure of the mouse CAR/RXR lbd heterodimer bound to tcpobop and 9CRA and a TIF2 peptide… | x-ray diffraction | A, B, C, D | — | — |
| 1XV9 | crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid, and… | x-ray diffraction | A, C | — | — |
| 1XV9 | Crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid, and… | x-ray diffraction | A, C | — | — |
| 1XVP | crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO | x-ray diffraction | A, C | — | — |
| 1XVP | Crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and citco | x-ray diffraction | A, C | — | — |
| 1YNW | Crystal Structure of Vitamin D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound… | x-ray diffraction | B | — | — |
| 1YNW | Crystal structure of vitamin D receptor and 9-cis retinoic acid receptor DNA-binding domains bound… | x-ray diffraction | B | — | — |
| 2ACL | Liver X-Receptor alpha Ligand Binding Domain with SB313987 | x-ray diffraction | A, C, E, G | — | — |
| 2ACL | Liver X-receptor alpha ligand binding domain with SB313987 | x-ray diffraction | A, C, E, G | — | — |
| 2NLL | Retinoid X receptor-thyroid hormone receptor DNA-binding domain heterodimer bound to thyroid… | x-ray diffraction | A | — | — |
| 2NLL | Retinoid X receptor-thyroid hormone receptor DNA-binding domain heterodimer bound to thyroid… | x-ray diffraction | A | — | — |
| 2P1T | Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with… | x-ray diffraction | A | — | — |
| 2P1T | Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with… | x-ray diffraction | A | — | — |
| 2P1U | Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with… | x-ray diffraction | A | — | — |
| 2P1U | Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with… | x-ray diffraction | A | — | — |
| 2P1V | Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with… | x-ray diffraction | A | — | — |
| 2P1V | Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with… | x-ray diffraction | A | — | — |
| 2ZXZ | Crystal structure of the human RXR alpha ligand binding domain bound to a synthetic agonist… | x-ray diffraction | A | — | — |
| 2ZXZ | Crystal structure of the human rxr alpha ligand binding domain bound to a synthetic agonist… | x-ray diffraction | A | — | — |
| 2ZY0 | Crystal structure of the human RXR alpha ligand binding domain bound to a synthetic agonist… | x-ray diffraction | A, C | — | — |
| 2ZY0 | Crystal structure of the human rxr alpha ligand binding domain bound to a synthetic agonist… | x-ray diffraction | A, C | — | — |
| 3DZU | Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic… | x-ray diffraction | A | — | — |
| 3DZU | Intact ppar gamma - rxr alpha nuclear receptor complex on DNA bound with BVT.13, 9-cis retinoic… | x-ray diffraction | A | — | — |
| 3DZY | Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with Rosiglitazone, 9-cis… | x-ray diffraction | A | — | — |
| 3DZY | Intact ppar gamma - rxr alpha nuclear receptor complex on DNA bound with rosiglitazone, 9-cis… | x-ray diffraction | A | — | — |
| 3E00 | Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with GW9662, 9-cis Retinoic… | x-ray diffraction | A | — | — |
| 3E00 | Intact ppar gamma - rxr alpha nuclear receptor complex on DNA bound with GW9662, 9-cis retinoic… | x-ray diffraction | A | — | — |
| 3E94 | Crystal structure of RXRalpha ligand binding domain in complex with tributyltin and a coactivator… | x-ray diffraction | A | — | — |
| 3E94 | Crystal structure of rxralpha ligand binding domain in complex with tributyltin and a coactivator… | x-ray diffraction | A | — | — |
| 3FAL | humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186 | x-ray diffraction | A, C | — | — |
| 3FAL | Humanrxr alpha & mouse lxr alpha complexed with retenoic acid and GSK2186 | x-ray diffraction | A, C | — | — |
117 records more on the page itself.
Ligands
- 9CR · (9cis)-retinoic acid · in 8 records
- ZN · Zinc ion · in 6 records
- CL · Chloride ion · in 5 records
- 9HF · 1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl) benzotriazole-5-carboxylic acid · in 4 records
- PO4 · Phosphate ion · in 3 records
- 4CU · (~{E})-3-[4-oxidanyl-3-(5-prop-2-enyl-2-propoxy-phenyl)phenyl]prop-2-enoic acid · in 2 records
- 7A4 · [(1Z)-5-fluoro-2-methyl-1-{[4-(propan-2-yl) phenyl]methylidene}-1H-inden-3-yl]acetic acid · in 2 records
- BR · Bromide ion · in 2 records
- CA · Calcium ion · in 2 records
- E8L · 6-[ethyl-[3-(2-methoxyethoxy)-4-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid · in 2 records
- E8O · 6-[ethyl-[4-(2-methylpropoxy)-3-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid · in 2 records
- I5W · (~{E})-3-[3-(2-methyl-5-phenyl-phenyl)-4-oxidanyl-phenyl]prop-2-enoic acid · in 2 records
- J57 · (~{E})-3-[4-oxidanyl-3-(3-propan-2-ylphenyl) phenyl]prop-2-enoic acid · in 2 records
- SJZ · (~{E})-3-[3-(2-methyl-3-phenyl-phenyl)-4-oxidanyl-phenyl]prop-2-enoic acid · in 2 records
- SO4 · Sulfate ion · in 2 records
- WY5 · 7-oxidanyl-2-oxidanylidene-6-(3,5,5,8,8-pentamethyl-6, 7-dihydronaphthalen-2-yl)chromene-3-carboxylic acid · in 2 records
- 754 · (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5, 6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid · in 1 record
- 7BE · (2~{R})-6,6,9,9-tetramethylspiro[3,4,7,8-tetrahydrobenzo[g]chromene-2,2'-3,4-dihydrochromene]-6'-carboxylic acid · in 1 record
- 7O0 · (~{E})-3-[4-oxidanyl-3-[3-(phenylmethyl) phenyl]phenyl]prop-2-enoic acid · in 1 record
- CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · in 1 record
- E80 · 6-[ethyl-[3-(2-methylpropoxy)-4-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid · in 1 record
- LFZ · 2-[4-[3,5-bis(trifluoromethyl)phenyl]phenyl]ethanoic acid · in 1 record
- LG2 · 6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid · in 1 record
- PLM · Palmitic acid · in 1 record
- T2K · 3-[5-[3,5-bis(chloranyl)phenyl]-4-phenyl-1,3-oxazol-2-yl]propanoic acid · in 1 record
- T72 · 3-(5-(3,5-bis(trifluoromethyl)phenyl)-4-phenyloxazol-2-yl)propanoic acid · in 1 record
- UGW · 2,4-di~{tert}-butylphenol · in 1 record
- WZ6 · 1-[3-(2-ethoxyethoxy)-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl]-2-(trifluoromethyl) benzimidazole-5-carboxylic acid · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.