MolNFT v1 · #151306 · protein
X-ray structure of a pentameric ligand gated ion channel from erwinia chrysanthemi (elic) 7'C pore mutant (L238C) in complex with nanobody 72
6HJX: “X-ray structure of a pentameric ligand gated ion channel from erwinia chrysanthemi (elic) 7'C pore mutant…”. X-ray diffraction, 2 ligands (PTY, NA). MolNFT v1 #151306 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6HJX
- Type
- protein
- Length
- 2,131 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0C7B7
- Ligands
- PTY, NA
Structure
x-ray diffraction · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 303 | — | P0C7B7 |
| B | — | protein | 309 | — | P0C7B7 |
| C | — | protein | 305 | — | P0C7B7 |
| D | — | protein | 302 | — | P0C7B7 |
| E | — | protein | 299 | — | P0C7B7 |
| F, J | — | protein | 124 | — | — |
| G | — | protein | 122 | — | — |
| H | — | protein | 122 | — | — |
| I | — | protein | 121 | — | — |
Ligands and binding sites
- PTY · Phosphatidylethanolamine · ligand · chains A, B
- NA · Sodium ion · metal
- LMT · Dodecyl-beta-D-maltoside · additive · 5 copies · chains A, E, B, C, D
- P6G · Hexaethylene glycol · additive · 4 copies · chains A, B, D, E
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6HJX · X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC)… · the same entry in another collection · chain J against J, TM-score 1.00
- P0C7B7 · AlphaFold monomer V2.0 prediction for cys-loop ligand-gated ion channel (P0C7B7) · a predicted model of the same protein · chain E against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C7B7
- Elsewhere: RCSB PDB 6HJX · PDBe 6HJX · UniProt P0C7B7
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